A novel chromatin immunoprecipitation and array (CIA) analysis identifies a 460-kb CENP-A-binding neocentromere DNA.

Lo AW, Magliano DJ, Sibson MC, Kalitsis P, Craig JM, and Choo KH
The Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Victoria, Australia 3052.

The estrogen receptor alpha (ERalpha) regulates gene expression by either direct binding to estrogen response elements or indirect tethering to other transcription factors on promoter targets. To identify these promoter sequences, we conducted a genome-wide screening with a novel microarray technique called ChIP-on-chip.

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